Okeeheelee Nature Center is located within Okeeleelee Park at 7715 Forest Hill Boulevard west of West Palm Beach.

From I-95, exit at Forest Hill Boulevard and head west. The entrance to Okeeheelee Park is located between Jog Road and the Turnpike overpass on the north side.Turn into the park and continue straight. The entrance to the nature center is just past the entrance to Pooch Pines Dog Park on the left side of the road. Turn left and proceed to the nature center parking lot.

From U.S. Highway 441, head east on Forest Hill Boulevard. The entrance to Okeeheelee Park is located between the Turnpike overpass and Jog Road on the north side.Turn into the park and continue straight. The entrance to the nature center is just past the entrance to Pooch Pines Dog Park on the left side of the road. Turn left and proceed to the nature center parking lot.